In the summer of 1712, María López, a teenage Maya girl in the Chiapas highlands, proclaimed to have spoken with an apparition of the Virgin Mary who told her that Spanish colonialism would soon end. By early August, thousands of Maya “soldiers of the Virgin,” rose up in the Tzeltal Revolt, one of the largest and most radical Indigenous revolts in Spanish America before 1750. Throughout the rebellion, María López continued to relay the Virgin’s directives, dressed in priestly vestments, and presided alongside newly ordained Maya Catholic priests. Lopez could neither read nor write, but I argue she acted as an Indigenous intellectual, navigating gender restrictions and establishing her prophetic authority through a keen awareness of the sociopolitical context of Chiapas’ Maya highlands and creative intellectual engagement with European and Maya Christian prophetic traditions.